CNS Disorders and Neuroimmunology - Hardcoverby Hugo Clifford (Editor) Central nervous system (CNS) disorders refer to a group of neurological disorders, which affect the function or structure of the spinal cord or brain, which together form the CNS. There are several symptoms associated with CNS disorders, such as loss of muscle strength, spasticity, persistent headache, slurred speech, seizures, paralysis, an inability to concentrate, increased reflexes, loss of feeling, tremors and memory